UBC CPD eLearning

Laser capture microdissection (LCM) is an automated sample preparation technique that allows the identification of specific substructures or cell types and their precise removal from the original tissue without causing damage. LCM has important advantages over other techniques for cell purification, especially in terms of precision, speed, simplicity and archiving capabilities. This technique of isolating pure samples from heterogeneous mixtures enables more efficient and accurate downstream microgenomics applications such as PCR, Sanger sequencing, next generation sequencing, proteomics and gene expression analysis.

Creative Bioarray is an expert in isolating specific cell populations from tissue sections using LCM and performing subsequent gene expression or DNA genotyping analysis. LCM, coupled with our ability to evaluate very limited quantities of RNA, can be used for target discovery, biomarker and safety assessment applications.